Some additional reading on Genetics (Module 4)

• Nucleic Acid Structure - Tutorial and problem set to help you understand the basics, as well as transcription and translation.
• Base-pairing tutorial for DNA replication, transcription, and protein synthesis - From PBS
• Home-made Genetics Animations
• Chromosome structure - how to pack 6 ft. of DNA into one of your cells.
• How evidence from chromosomes supports the conclusion that humans and modern apes had a common ancestor - A video from Jeremy Mohn
• Meiosis - an excellent animation to help you master this difficult concept
• Chapter on Mendelian Genetics (from the MIT Biology Hypertextbook 7.01), with some practice problems
• Predict the coat color of your Labrador puppies - A genetic testing service for dog breeders!
• Problem sets
• More monohybrid cross problems - a very nice problem set, with tutorial help if you get the wrong answer! From the U of Arizona (caution: sometimes this link is quite slow)
• More dihybrid cross problems - as above, from the University of Arizona
• Genetics Practice Problems - KSU Biology: Our own Eva Horne has prepared a set of problems for BIOL 198 students, with vocabulary help and helpful hints.
• Online Mendelian Inheritance in Man -  Online library of human genetic disorders, their diagnosis, prognosis, and background. Very thorough and with many literature citations for further study
• Scientists are trying to treat type A or type B blood so that transfusions can be made safer! An article from Science News with a lot of background on the ABO blood type system.
• Hemoglobin and Sickle Cell Anemia
• Hemoglobin - learn about this molecule, and how it is affected by the sickle-cell mutation
• Normal red blood cells and Sickled red blood cells - Microscopic views from the University of Utah Med Center. Y
• A case study - diagnosis of sickle cell disease in a 24 year old man. From Washington University Medical School.
• Mechanisms of speciation, and examples of macroevolution which have been observed.
• Problem set for Hardy-Weinberg equilibrium - Interactive and very helpful!
• Computer model for Genetic Drift - see how random changes can radically affect gene frequencies.
• Computer model for Natural Selection - see how selection can affect gene frequencies over time.
• Many other excellent and interactive simulations of population genetics phenomena!

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Kansas State University
November 5, 2009