http://www.ksu.edu/biology K-State Division of Biology

Upton

 

Steve J. Upton

Professor

Ph.D. 1983, Auburn University.
Parasitology

Systematics, life cycles, biochemistry, and molecular biology of coccidia; development of protozoa in vitro, in ovo, and in vivo; protozoology; parasite immunology.

347 Ackert Hall
(785) 532-6639
coccidia@ksu.edu

Curriculum Vita
KSU Parasitology Laboratory - information on Cryptosporidium research here at KSU


Research Focus

Molecular and cellular biology of Cryptosporidium; development of coccidia in vivo, in ovo, and in vitro; parasite/host cell interactions; screening of pharmaceuticals against protozoan parasites in vitro; systematics of coccidia

Selected Research Publications

Duszynski, D.W., Bolek, M.G., and Upton, S.J. 2007. Coccidia (Apicomplexa: Eimeriidae) of amphibians of the world. Zootaxa 1667: 1-77.

Woods, K.M. and Upton, S.J. 2007. In vitro development of Cryptosporidium parvum in serum-free media. J. Appl. Microbiol. 44: 520-523.

Yarlett, N., G. Wu, W.R. Waters, J.A. Harp, M.J. Wannemuehler, M. Morada, D. Athanasopoulos, S.J. Upton, L.J. Marton, and B.J. Frydman. 2007. Cryptosporidium parvum spermidine/spermine N1-acetyltransferase exhibits different characteristics from the host enzyme. Mol Biochem Parasitol. 152(2): 170-80.

Yarlett, N., W.R. Waters, J.A. Harp, M.J. Wannemuehler, M. Morada, J. Bellcastro, S.J. Upton, L.J. Marton, and B.J. Frydman. 2007. Activities of DL-alpha-difluoromethylarginine and polyamine analogues against Cryptosporidium parvum infection in a T-cell receptor alpha-deficient mouse model. Antimicrob Agents Chemother. 51(4): 1234-9.

Xiao, L., R. Fayer, U. Ryan, and S.J. Upton. 2007. Response to the newly proposed species Cryptosporidium pestis. Trends Parasitol. 23(2): 41-2.

Rochelle, P.A., D. Faller, M.M. Marshall, B.A. Montelone, S.J. Upton, and K. Woods. 2004. Irreversible UV inactivation of Cryptosporidium spp. despite the presence of UV repair genes.  J. Euk. Microbiol. 51: 553-562.

Palmer, C.J., Xiao, L., Terashima, A., Guerra, H., Gotuzzo, E., Saldias, G., Bonilla, J.A., Zhou, L., and Upton, S.J. 2003. Cryptosporidium muris, a rodent pathogen recovered from a human in Peru.  Emerg. Inf. Dis. 9: 1174-1176.

Khramtsov, N.V., K.M. Woods, M.V. Nesterenko, C.C. Dykstra, and S.J. Upton. 1997. Virus-like double-stranded RNAs in the parasitic protozoan, Cryptosporidium parvum. Mol. Microbiol. 26(2): 289-300.



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