Wang, H. and R.J. Clem. 2011. The role of IAP antagonists in the core apoptosis pathway of the mosquito disease vector Aedes aegypti. Apoptosis. In press.
Kanost, M.R. and R.J. Clem. 2011. Insect proteases. In Comprehensive Molecular Insect Science, Vol. 4: Biochemistry and Molecular Biology. L.I. Gilbert, K. Iatrou, and S. Gill, eds. Elseveir. In press.
Liu, Q. and R.J. Clem. 2010. Defining the core apoptosis pathway in the mosquito disease vector Aedes aegypti: the roles of iap1, ark, dronc, and effector caspases. Apoptosis. DOI: 10.1007/s10495-010-0558-9.
Clem, R.J., Popham, H., and Shelby, K. 2010. Antiviral responses in insects: Apoptosis and humoral responses. In Insect Virology, S. Asgari and K. Johnson, eds. Caister Academic Press. Norfolk, UK, pp 389-410.
Bartholomay, L.C., Waterhouse, R.M., Mayhew, G.F., Campbell, C.L., Michel, K., Zou, Z., Ramirez, J.L., Das, S., Alvarez, K., Arensburger, P., Bryant, B., Chapman, S.B., Dong, Y., Erickson, S.M., Parakrama Karunaratne, S.H.P., Kokoza, V., Kodira, C.D., Pignatelli, P., Shin, S.W., Vanlandingham, D.L., Atkinson, P.W., Birren, B., Christophides, G.K., Clem, R.J., Hemingway, J., Higgs, S., Megy, K., Ranson, H., Zbodnov, E.M., Raikhel, A.S., Christensen, B.M., Dimopoulos, G., and M.A.T. Muskavitch. 2010. Pathogenomics of Culex quinquefasciatus and meta-analysis of infection responses to diverse pathogens. Science 330:88-90.
Bryant, B., Ungerer, M.C., Waterhouse, R.W., Liu, Q., and R.J Clem. A caspase-like decoy molecule enhances the activity of a paralogous caspase in the yellow fever mosquito, Aedes aegypti. Insect Biochem. Molec. Biol. 40:516-523.
Bryant, B. and R.J. Clem. 2009. The caspase inhibitor P35 is required for the production of robust baculovirus virions in Trichoplusia ni TN-368 cells. J. Gen. Virol. 90:654-661.
Bryant, B., Zhang, Y., Zhang, C., Santos, C.P., Clem, R.J., and L. Zhou. 2009. A Lepidopteran ortholog of reaper reveals functional conservation and evolution of IAP antagonists. Insect Molec. Biol. 18:341-351.
Bryant, B., C.D. Blair, K.E. Olson, and R.J. Clem. 2008. Annotation and expression profiling of apoptosis-related genes in the yellow fever mosquito, Aedes aegypti. Insect Biochem. Molec. Biol. 38:331-345.
Clem, R.J. 2008. Baculovirus apoptosis inhibitors. In Encyclopedia of Virology, Third edition. B.W.J. Mahy
and M.H.V. Van Regenmortel, Eds. Oxford: Elsevier. Vol. 1, pp 231-237.
Means, J.C. and R.J. Clem. 2008. Evolution and function of the P35 family of apoptosis inhibitors. Future
Virology 3:383-391.
Wang, H., C.D. Blair, K.E. Olson, and R.J. Clem. 2008. Effect of inducing or inhibiting apoptosis on Sindbis virus replication in mosquito cells. J. Gen. Virol. 89:2651-2661.
Clem, R.J. 2007. Baculoviruses and apoptosis: A diversity of genes and responses. Curr. Drug Targets 8:1069-1074.
Means, J.C., T. Penabaz, and R.J. Clem. 2007. Identification and functional characterization of AMVp33, a novel
homolog of the baculovirus caspase inhibitor p35 found in Amsacta moorei entomopoxvirus. Virology 358:446-457.
Deng, Y., Y. Dong, V. Thodima, R.J. Clem, and A.L. Passarelli. 2006. Analysis and functional annotation of
expressed sequence tags from the fall armyworm Spodoptera frugiperda. BMC Genomics 7:264. doi:10.1186/1471-2164-7-264.
Means, J.C., I. Muro, and R.J. Clem. 2006. Lack of involvement of mitochondrial factors in caspase activation in
a Drosophila cell-free system. Cell Death Differ. 13:1222-1234.
Clem, R.J. 2005. The role of apoptosis in defense against baculovirus infection in insects. Curr. Top. Microbiol. Immunol. 289:113-130.
Muro, I., J.C. Means, and R.J. Clem. 2005. Cleavage of the apoptosis inhibitor DIAP1 by the apical caspase
DRONC in both normal and apoptotic Drosophila cells. J. Biol. Chem. 280:18683-18688.
Wright, C.W., J.C. Means, T. Penabaz, and R.J. Clem. 2005. The baculovirus anti-apoptotic protein Op-IAP
does not inhibit Drosophila caspases or apoptosis in Drosophila S2 cells and instead sensitizes S2 cells to virus-induced apoptosis. Virology 335:61-71.
Green, M.C., K.P. Monser, and R.J. Clem. 2004. Ubiquitin protein ligase activity of the anti-apoptotic baculovirus protein Op-IAP3. Virus Res. 105:89-96.
Muro, I., K. Monser, and R.J. Clem. 2004. Mechanism of Dronc activation in Drosophila cells. J. Cell Sci. 117:5035-5041.
Clarke, T.E. and R.J. Clem. 2003. Insect defenses against virus infection: The role of apoptosis. Int. Rev. Immunol. 22:401-424.
Clarke, T.E. and R.J. Clem. 2003. In vivo induction of apoptosis correlating with reduced infectivity during baculovirus infection. J. Virol. 77:2227-2232.
Means, J.C., I. Muro, and R.J. Clem. 2003. Silencing of the baculovirus Op-iap3 gene by RNA interference reveals that it is required for preventing apoptosis during Orgyia pseudotsugata M nucleopolyhedrovirus infection of Ld652Y cells. J. Virol. 77:4481-4488.
Clarke, T.E. and R.J. Clem. 2002. Lack of involvement of hemocytes in the establishment and spread of infection in Spodoptera frugiperda larvae infected with the baculovirus AcMNPV by intrahemocoelic injection. J. Gen. Virol. 83:1565-1572.
Clem, R. J. 2001. Baculoviruses and apoptosis: The good, the bad, and the ugly. Cell Death and Differentiation 8:137-143.
Muro, I., Hay, B.A., and R.J. Clem. 2002. The Drosophila DIAP1 protein is required to prevent accumulation of a continuously generated, processed form of the apical caspase DRONC. J. Biol. Chem. 277:49644-49650.
Wright, C.W. and R.J. Clem. 2002. Sequence requirements for Hid binding and apoptosis regulation in the baculovirus inhibitor of apoptosis Op-IAP: Hid binds Op-IAP in a manner similar to Smac binding of XIAP. J. Biol. Chem. 277:2454-2462.
Yoo, S.J., Huh, J.R., Muro, I., Yu, H., Wang, L., Wang, S.L., Feldman, R.M.R., Clem, R.J., Muller, H.-A.J., and B.A. Hay. 2002. Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms. Nature Cell Biol. 4:416-424.
